22Rx

Discovery from first principles

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The Experiment

We built a system that discovers drugs
without knowing medicine exists.

No training data. No medical literature. No FDA records.
Just physics, chemistry, and the mathematics of healing.

Bipolar Disorder

180 million molecules.
63 emerged.

63
Candidates with 100% virtual efficacy
35
Minutes to process

Among them: Carbamazepine. FDA-approved in 1974.
The system had never heard of it.

Carbamazepine FDA 1974
Memantine Clinical
Inositol Validated
GSK3B Lithium Target
Alzheimer's Disease

One thousand compounds.
Two of them already exist.

1,000
Candidates discovered

Donepezil and Memantine—the only two FDA-approved Alzheimer's drug classes. Rediscovered from pure mathematics.

Donepezil #1 Prescribed
Memantine #2 Prescribed
Sigma Receptors 2024 Trials
AChE Inhibitors Drug Class

It didn't read the papers.
It rediscovered them.