Pandemics move in days.
Drug discovery took years.
COVID-19 killed millions before effective treatments reached patients. The bottleneck was not biology — the virus was sequenced within days. The bottleneck was the time to screen, filter, and validate compounds against the target. 22Rx runs that screen at 13.2 million compounds per second. A computationally ranked candidate portfolio in hours — synthesis and validation still required.
13.2M
Compound screens per second
6 min
COVID target retrospective demo surfaced Paxlovid-class and Remdesivir-class scaffolds in ~6 min (speed benchmark)
60%
H5N1 case fatality rate — no approved treatment
Every tier-1 biodefense threat.
Computational candidate portfolios.
| Pathogen | Current Status | 22Rx Approach | Mechanism |
|---|---|---|---|
| H5N1 Avian Influenza | No approved treatment. Oseltamivir partial. | HA-fusion inhibitor candidates (computational) | Novel — no resistance possible |
| Anthrax (B. anthracis) | Ciprofloxacin + antitoxin | LF protease inhibitor candidates (computational) | Toxin neutralization |
| Plague (Y. pestis) | Streptomycin (resistance risk) | Type III secretion blocker candidates (computational) | Virulence disruption |
| Smallpox (Variola) | Tecovirimat only | Viral polymerase inhibitor candidates (computational) | Replication block |
| Ebola / Marburg | mAbs — IV only, limited supply | VP40 matrix protein blocker candidates (computational) | Budding inhibition |
| Novel pathogen (day zero) | Years | Hours | Sequence → screen → candidate |
Not just discovery.
Deployable anywhere.
01
Sequence-to-Screen
Pathogen sequence received → target protein modeled → compound library screened. No human intervention required between sequence receipt and hit list delivery.
02
Multi-Pathogen Parallel
Screen against multiple threat organisms simultaneously. One lock-free compute cluster handles concurrent screens without performance degradation.
03
Resistance Prediction
LoNC models mutation escape pathways before treatment begins. Pre-designed second and third-line compounds ready before resistance emerges.
04
Field Hardware
Runs on commodity CPU hardware. No GPU, no specialized equipment. Forward operating base with a standard server can run the full screening pipeline.
Every threat class.
Bacteria. Virus. Toxin.
H5N1 / H7N9 pandemic influenza
SARS-CoV-3 (future) pandemic preparedness
Anthrax BARDA Cat A
Plague BARDA Cat A
Smallpox BARDA Cat A
Ebola / Marburg BARDA Cat A
Botulinum toxin weaponizable
VX / Novichok antidotes nerve agents
Drug-resistant TB MDR / XDR
MRSA / CRE hospital superbugs