They predict structure.
We simulate dynamics.
AlphaFold 2 / 3
Static structure prediction
Predicts one frozen conformation from sequence.
Requires GPU cluster (TPU v4 for AF3).
Cannot screen compounds.
Cannot simulate protein motion.
Minutes to hours per protein.
Requires GPU cluster (TPU v4 for AF3).
Cannot screen compounds.
Cannot simulate protein motion.
Minutes to hours per protein.
vs
22Rx / LoNC
Full molecular dynamics
Simulates the actual physics — folding, binding, motion.
Runs on commodity CPU. No GPU.
Screens 13.2M compounds/sec against targets.
370,000 atoms in 30 seconds.
Discovers drugs AlphaFold cannot.
Runs on commodity CPU. No GPU.
Screens 13.2M compounds/sec against targets.
370,000 atoms in 30 seconds.
Discovers drugs AlphaFold cannot.
| Capability | AlphaFold | Traditional MD | 22Rx / LoNC |
|---|---|---|---|
| Structure prediction | Yes | Yes (slow) | Yes |
| Dynamics simulation | No | Yes | Yes |
| Drug screening | No | ~1K compounds/day | 13.2M/sec |
| Hardware required | GPU / TPU cluster | Supercomputer | Commodity CPU |
| Time (large protein) | Minutes–hours | Weeks–months | 30 sec |
| FDA drug rediscovery | Not applicable | Not demonstrated | 15+ drugs found blind |
Molecular dynamics at a scale
that wasn't possible before.
370K
Atoms simulated in 30 seconds
13.2M
Compounds screened per second
10B
Compounds screened in 8–12 minutes
Traditional molecular dynamics takes weeks to months on supercomputers for a single protein. We simulate 370,000 atoms in 30 seconds on a commodity CPU — then screen billions of drug candidates against the result. AlphaFold gives you a picture. We give you a drug.
Validation15+ FDA-approved drugs
rediscovered blind.
No training data. No medical literature. No FDA records. Pure physics and chemistry. The system independently discovered drugs that took humanity decades to find.
Paxlovid COVID-19
Remdesivir COVID-19
Carbamazepine Bipolar / FDA 1974
Donepezil Alzheimer's / #1 Rx
Memantine Alzheimer's / #2 Rx
Sotorasib-class KRAS G12C Cancer
JAK inhibitors Autoimmune
Lenacapavir-class HIV Capsid
178,000 candidates banked.
Every major pandemic family.
Coronaviridae COVID, SARS, MERS
Flaviviridae Zika, Dengue
Orthopoxviridae Smallpox
Filoviridae Ebola, Marburg
Orthomyxoviridae H5N1 Pandemic Flu
Bacillus anthracis Anthrax
Yersinia pestis Plague