The same drug. Different patients.
Wildly different outcomes.
Medicine is still largely population-based. A drug that works for 60% of patients is approved. The 40% who don't respond — or who have serious adverse reactions — are identified after the fact. Your CYP2D6 genotype determines whether codeine gives you analgesia or respiratory failure. Your HLA type determines whether abacavir triggers a potentially fatal hypersensitivity reaction. These interactions are knowable before the prescription is written. They just haven't been screened in time.
174×
Faster than BWA-MEM + GATK genomics pipeline
7M
US hospitalizations annually from adverse drug reactions
<8 min
Whole genome analyzed on commodity hardware
Every variable. One profile.
Before the first dose.
| Screen | What It Catches | Current Standard | 22Rx Approach |
|---|---|---|---|
| Pharmacogenomics (PGx) | Drug metabolism variants (CYP2D6, CYP2C19, TPMT) | Panel test, days | Genome-wide, minutes |
| Adverse reaction risk | HLA-B*57:01 (abacavir), HLA-B*15:02 (carbamazepine) | Specific allele test | Full HLA typing, simultaneous |
| Disease risk stratification | BRCA, Lynch syndrome, cardiac channelopathies | Targeted panels | Whole genome variant calling |
| Vaccine safety pre-screen | Myocarditis risk (mRNA vaccines), prior immunity | Not routinely done | Pre-administration profile |
| Unified point-of-care profile | All of the above, simultaneously | Days–weeks, fragmented | <10 min, single report |
Any setting.
Any patient. Any drug.
01
Emergency Medicine
Unconscious patient arrives. Unknown drug history. Genome screened for drug interactions in minutes before any IV medication is administered.
02
Oncology Treatment Selection
Tumor genomics + patient germline combined. Which chemotherapy this tumor will respond to. Which the patient can metabolize. Matched in real time.
03
Warfighter Medicine
Forward-deployed genomic screening. Every warfighter's PGx profile available before trauma care. Morphine dose. Antibiotic choice. Blood thinner compatibility. No guessing.
04
Population Surveillance
Pandemic-scale genomic screening — identify high-risk individuals for emerging pathogens or vaccines before exposure. Runs on commodity hardware at national scale.
Every drug class.
Every medical domain.
Oncology tumor + germline matched
Cardiology anticoagulants / statins
Psychiatry antidepressants / antipsychotics
Infectious disease antibiotic / antiviral dosing
Pain management opioid metabolism (CYP2D6)
Transplant immunosuppressant matching
Pediatrics neonatal drug safety
Vaccine safety pre-administration HLA screen